The Sequencing Initiative Suomi (SISu) search engine offers a way to search for data on sequence variants in Finns. It provides valuable summary data for researchers and clinicians as well as other people having an interest in genetics in Finland. With SISu, you can examine the attributes and appearance of different variants in Finnish cohorts and see their aggregate distribution in Finland visualized on a map. In the current version users can search for summary data on single nucleotide variants and indels from exomes of over 10 000 individuals sequenced in disease-specific and population genetic studies. The SISu project is an international collaboration between multiple research groups aiming to build tools for genomic medicine. The first version of the SISu search engine was released in 2014. The project is coordinated in the Institute for Molecular Medicine Finland (FIMM) at the University of Helsinki.